PerturbAI Brain Wide In Vivo CRISPR Atlas This dataset represents a landmark in functional genomics: spanning 8 million single cells in living tissue and hundreds of distinct neuronal cell types, this is the most expansive in vivo functional genomics resource ever created. By mapping the language of biology at an unprecedented scale, our platform provides the foundation for the next generation of AI driven therapeutic discovery. Manuscript: “Genome scale functional mapping of the mammalian whole brain with in vivo Perturb seq” on bioRxiv Summary: Check out our blog www.perturb.ai/news Data: Download the full dataset on Hugging Face Analysis: Explore the dataset with the NVIDIA AI Blueprint for Single Cell Analysis that leverages scverse’s RAPIDS singlecell on RTX PRO 6000 Blackwell Workstation Edition, helping PerturbAI speed up analysis from days to near real time (link) Dataset Description Using large scale CRISPR screening and single nucleus RNA sequencing, we’ve built a functional map of the mouse brain's genome. Measuring the effects of nearly 2,000 disease linked genes in their native environment, we’ve revealed the molecular logic of the neuronal circuits underlying neurodeg…
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