OpenTME: Open Access Tumor Microenvironment Profiles from TCGA OpenTME is an open access project by Aignostics for academic researchers. It provides comprehensive spatial outputs for whole slide images (WSIs) of formalin fixed, paraffin embedded slides from The Cancer Genome Atlas (TCGA). OpenTME is powered by Atlas H&E TME – a computational pathology application developed by Aignostics. Atlas H&E TME Atlas H&E TME is a foundation model based application for spatial profiling of H&E images. It was built with Atlas , an industry leading pathology foundation model co developed by Aignostics, Mayo Clinic, LMU Munich, and Charité Berlin. Atlas H&E TME is used by leading Life Sciences companies to support translational and clinical research efforts; OpenTME is the first open access version available for academic researchers. Dataset Description OpenTME provides pre computed spatial readouts in .csv format. For each WSI, the dataset contains detailed quantitative measurements derived from Atlas H&E TME's four stage analysis pipeline: tissue quality control, tissue segmentation, cell detection / classification, and neighborhood analysis. Readouts for each WSI include: QC metrics: Area and…
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